Visceral larva migrans

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Visceral larva migrans
Classification and external resources
Specialty infectious disease
ICD-10 B83.0
ICD-9-CM 128.0
DiseasesDB 13882
MedlinePlus 000633
eMedicine ped/2407
MeSH D007816
[edit on Wikidata]

Visceral larva migrans (VLM) is a condition in humans caused by the migratory larvae of certain nematodes, humans being a dead-end host, and was first reported in 1952.[1] Nematodes causing such zoonotic infections are Baylisascaris procyonis,[2] Toxocara canis,[3] Toxocara cati,[3] and Ascaris suum.[4] These nematodes can infect but not mature in humans and after migrating through the intestinal wall, travel with the blood stream to various organs where they cause inflammation and damage. Affected organs can include the liver, heart (causing myocarditis) and the CNS (causing dysfunction, seizures, and coma). A special variant is ocular larva migrans where usually T. canis larvae travel to the eye.

Only a few roundworm eggs are necessary to cause larva migrans in the human child or adult. However, visceral larva migrans seems to affect children aged 1–4 more often while ocular larva migrans more frequently affects children aged 7–8. Between 4.6% and 23% of U.S. children have been infected with the dog roundworm egg. This number is much higher in other parts of the world, such as Colombia, where up to 81% of children have been infected.[5]

Cutaneous larva migrans is a condition where nematodes such as Ancylostoma braziliense migrate to the skin.

A list of causative agents of larva migrans syndromes is not agreed upon and varies with the author.[6]

See also


  1. ^ Beaver, P. C.; Snyder, C. H.; Carrera, G. M.; Dent, J. H.; Lafferty, J. W. (1952). "Chronic eosinophilia due to visceral larva migrans; report of three cases". Pediatrics. 9 (1): 7–19. PMID 14911260. 
  2. ^ Gavin, P. J.; Kazacos, K. R.; Shulman, S. T. (2005). "Baylisascariasis". Clinical Microbiology Reviews. 18 (4): 703–18. doi:10.1128/CMR.18.4.703-718.2005. PMC 1265913Freely accessible. PMID 16223954. 
  3. ^ a b Beaver, PC (1959). "Visceral and cutaneous larva migrans". Public Health Reports. 74 (4): 328–32. doi:10.2307/4590442. PMC 1929226Freely accessible. PMID 13645880. 
  4. ^ Sakai, S.; Shida, Y.; Takahashi, N.; Yabuuchi, H.; Soeda, H.; Okafuji, T.; Hatakenaka, M.; Honda, H. (2006). "Pulmonary Lesions Associated with Visceral Larva Migrans Due to Ascaris suum or Toxocara canis: Imaging of Six Cases". American Journal of Roentgenology. 186 (6): 1697–1702. doi:10.2214/AJR.04.1507. PMID 16714661. 
  5. ^ Artem Cheprasov. 2012. Death at the Playground. Guru Magazine. 11. pp. 59-61.
  6. ^ Iowa State University (May 2005). "Larva migrans" (PDF). Retrieved November 10, 2010. 

Retrieved from ""
This content was retrieved from Wikipedia :
This page is based on the copyrighted Wikipedia article "Visceral larva migrans"; it is used under the Creative Commons Attribution-ShareAlike 3.0 Unported License (CC-BY-SA). You may redistribute it, verbatim or modified, providing that you comply with the terms of the CC-BY-SA