Tabernanthine

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Tabernanthine
Skeletal formula of tabernanthine
Ball-and-stick model of the tabernanthine molecule
Clinical data
ATC code
  • none
Identifiers
CAS Number
  • 83-94-3
PubChem CID
  • 6326116
ChemSpider
  • 4885254
UNII
  • TV52I1S16D
Chemical and physical data
Formula C20H26N2O
Molar mass 310.43 g/mol
3D model (JSmol)
  • Interactive image

Tabernanthine is an alkaloid found in Tabernanthe iboga.[1]

It has been used in laboratory experiments to study how addiction affects the brain.[2]

Tabernanthine persistently reduced the self-administration of cocaine and morphine in rats.[3]

See also

References

  1. ^ Bartlett, M. F.; Dickel, D. F.; Taylor, W. I. (1958). "The Alkaloids of Tabernanthe iboga. Part IV.1 The Structures of Ibogamine, Ibogaine, Tabernanthine and Voacangine - Journal of the American Chemical Society (ACS Publications)". Journal of the American Chemical Society. 80: 126–136. doi:10.1021/ja01534a036.
  2. ^ Levi MS, Borne RF (October 2002). "A review of chemical agents in the pharmacotherapy of addiction". Curr. Med. Chem. 9 (20): 1807–18. doi:10.2174/0929867023368980. PMID 12369879.
  3. ^ Glick SD, Kuehne ME, Raucci J, Wilson TE, Larson D, Keller RW Jr, Carlson JN (September 1994). "Effects of iboga alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum". Brain Res. 657 (1–2): 14–22. doi:10.1016/0006-8993(94)90948-2. PMID 7820611.


Retrieved from "https://en.wikipedia.org/w/index.php?title=Tabernanthine&oldid=874673098"
This content was retrieved from Wikipedia : http://en.wikipedia.org/wiki/Tabernanthine
This page is based on the copyrighted Wikipedia article "Tabernanthine"; it is used under the Creative Commons Attribution-ShareAlike 3.0 Unported License (CC-BY-SA). You may redistribute it, verbatim or modified, providing that you comply with the terms of the CC-BY-SA