Rolf Huisgen

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Rolf Huisgen
Rolf Huisgen and Franz Marc's Mandrill.JPG
Rolf Huisgen (2004) in front of the painting "Mandrill" by Franz Marc
Born (1920-06-13) 13 June 1920 (age 98)
Gerolstein, Rhineland-Palatinate, Germany
Nationality German
Alma mater University of Munich
Known for 1,3-Dipolar cycloaddition
Awards 1961 Liebig Medal
1979 Otto Hahn Prize for Chemistry and Physics
Scientific career
Fields Chemist
Institutions University of Munich
Doctoral advisor Heinrich Otto Wieland

Rolf Huisgen (born 13 June 1920) is a German chemist. He was born in Gerolstein in the Rhineland-Palatinate and studied in Munich under the supervision of Heinrich Otto Wieland. After completing his Ph.D. in 1943 and his habilitation in 1947, he was named professor at the University of Tübingen in 1949. He returned to the University of Munich in 1952 where he remained dedicated to research long after attaining emeritus status in 1988.[1]

One of his major achievements was the development of the 1,3-Dipolar cycloaddition reaction, also known as the Huisgen cycloaddition or Huisgen reaction.[2][3] The Huisgen reaction is of paramount importance to the synthesis of heterocyclic compounds. His importance in synthetic organic chemistry, however, extends to the enormous influence he had in post-war chemistry departments in Germany and Austria, due to the large number of his "habilitants" becoming professors. Ivar Karl Ugi, Johann Mulzer, Bernd Giese, Johann Gasteiger, Herbert Mayr (Chemist), Hans-Ulrich Reissig, Jürgen Sauer and Reinhard Brückner are but a few of them.


  1. ^ Jeffrey I. Seeman (2005). "Rolf Huisgen: A Gentleman Scholar with Energy and Passion". Helvetica Chimica Acta. 88 (6): 1145–1153. doi:10.1002/hlca.200590097. 
  2. ^ Huisgen, Rolf (November 1963). "Kinetics and Mechanism of 1,3-Dipolar Cycloadditions". Angewandte Chemie International Edition. 2 (11): 633–645. doi:10.1002/anie.196306331. 
  3. ^ Huisgen, Rolf (October 1963). "1,3-Dipolar Cycloadditions. Past and Future". Angewandte Chemie International Edition. 2 (10): 565–598. doi:10.1002/anie.196305651. 


  • Rüchardt, Christoph; Sauer, Jürgen; Sustmann, Reiner (2005). "Rolf Huisgen: Some Highlights of His Contributions to Organic Chemistry". Helvetica Chimica Acta. 88 (6): 1154. doi:10.1002/hlca.200590098. 
  • Houk, Kendall N. (2010). "Rolf Huisgen's Profound Adventures in Chemistry". Helvetica Chimica Acta. 93 (7): 1241. doi:10.1002/hlca.201000209. 

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