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Clinical data
Synonyms 6α,9α-Difluoro-11β,16α,17α,21-tetrahydroxypregn-4-ene-3,20-dione, cyclic (R)-16,17-acetal with butyraldehyde; 16α,17α-[(1R)-butylidenebis(oxy)]-6α,9α-difluoro-11β,21-dihydroxypregn-4-ene-3,20-dione
Drug class Corticosteroid; Glucocorticoid
CAS Number
  • 144459-70-1
PubChem CID
  • 3055174
  • 2316734
  • R9IQ7GVL3E
Chemical and physical data
Formula C25H34F2O6
Molar mass 468.54 g·mol−1
3D model (JSmol)
  • Interactive image

Rofleponide is a synthetic glucocorticoid corticosteroid which was never marketed.[1][2][3][4]


  1. ^ "Rofleponide". AdisInsight.
  2. ^ Ahlström-Emanuelsson C, Andersson M, Persson C, Schrewelius C, Greiff L (2004). "Topical treatment with aqueous solutions of rofleponide palmitate and budesonide in a pollen-season model of allergic rhinitis". Clin. Exp. Allergy. 34 (5): 731–5. doi:10.1111/j.1365-2222.2004.1965.x. PMID 15144464.
  3. ^ K Nagaraju (30 November 2013). Manual of Pediatric Allergy. JP Medical Ltd. pp. 109–. ISBN 978-93-5090-498-5.
  4. ^ Jonathan A. Bernstein (27 May 2016). Rhinitis, An Issue of Immunology and Allergy Clinics of North America, E-Book. Elsevier Health Sciences. pp. 407–. ISBN 978-0-323-44468-2.

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