Promazine

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Promazine
Promazine.svg
Promazine3d.png
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
MedlinePlus a600010
ATC code
Pharmacokinetic data
Protein binding 94%
Elimination half-life 20-40 hr
Identifiers
CAS Number
  • 58-40-2 ☑Y
PubChem CID
  • 4926
IUPHAR/BPS
  • 7281
DrugBank
  • DB00420 ☑Y
ChemSpider
  • 4757 ☑Y
UNII
  • O9M39HTM5W
ChEBI
  • CHEBI:8459 ☑Y
ChEMBL
  • CHEMBL564 ☑Y
ECHA InfoCard 100.000.347
Chemical and physical data
Formula C17H20N2S
Molar mass 284.42 g/mol
3D model (JSmol)
  • Interactive image
  (verify)

Promazine (brand name Sparine) is a medication that belongs to the phenothiazine class of antipsychotics. An older medication used to treat schizophrenia, it is still prescribed, alongside newer agents such as olanzapine and quetiapine. It has predominantly anticholinergic side effects, though extrapyramidal side effects are not uncommon either.

Promazine is not approved for human use in the United States. It is available in the US for veterinary use under the names Promazine and Tranquazine.

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