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Clinical data
Synonyms (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylidene-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-one
ATC code
CAS Number
  • 599-33-7 ☒N
PubChem CID
  • 20055008
  • 16735979 ☑Y
  • IF8PQP966U
ECHA InfoCard 100.009.060
Chemical and physical data
Formula C22H28O5
Molar mass 372.455 g·mol−1
3D model (JSmol)
  • Interactive image
 ☒N☑Y (what is this?)   (verify)

Prednylidene is a glucocorticoid[1] for systemic use.

Substitution at position 16 also leads to more potent corticosteroids. The additional steric bulk introduced by such substituents adjacent to the dihydroxyacetone side chain also protects that moiety against metabolic degradation.


  1. ^ Buttgereit F, Brand MD, Burmester GR (July 1999). "Equivalent doses and relative drug potencies for non-genomic glucocorticoid effects: a novel glucocorticoid hierarchy". Biochem. Pharmacol. 58 (2): 363–8. doi:10.1016/S0006-2952(99)00090-8. PMID 10423179.

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