Pirlimycin

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Pirlimycin
Structural formula
Space-filling model of pirlimycin molecule
Clinical data
Routes of
administration
Intramammary
ATCvet code
Identifiers
CAS Number
  • 79548-73-5 ☑Y
ChemSpider
  • 138508 ☒N
UNII
  • LM19JT6G5K
KEGG
  • D08391 ☑Y
ChEMBL
  • CHEMBL1652611 ☒N
Chemical and physical data
Formula C17H31ClN2O5S
Molar mass 410.164 g/mol
3D model (JSmol)
  • Interactive image
 ☒N☑Y (what is this?)   (verify)

Pirlimycin hydrochloride belongs to the lincosamide class of antimicrobials. Under the trade name Pirsue,[1] it is used in the treatment of mastitis in cattle.

Activity

Pirlimycin is active against Gram-positive bacteria, specifically Staphylococcus aureus and coagulase negative species of Staphylococcus and Streptococcus. It has no activity against Gram-negative bacteria.[2]

Mechanism of action

It is bacteriostatic and acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome.

References

  1. ^ Pirsue Sterile Solution
  2. ^ USP: Pirlimycin


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