Perazine

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Perazine
Perazine.svg
Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Identifiers
CAS Number
  • 84-97-9 YesY
PubChem CID
  • 4744
ChemSpider
  • 4582 No
UNII
  • 8915147A2B
ChEBI
  • CHEBI:59118 No
ECHA InfoCard 100.001.435
Chemical and physical data
Formula C20H25N3S
Molar mass 339.498 g/mol
3D model (JSmol)
  • Interactive image
 NoYesY (what is this?)  (verify)

Perazine (Taxilan) is a moderate-potency typical antipsychotic of the phenothiazine class. It is quite similar to chlorpromazine, and acts as a dopamine antagonist. A 2014 systematic review compared it with other antipsychotic drugs:

Perazine versus other antipsychotic drugs for schizophrenia[1]
Summary
The number, size and reporting of randomized controlled perazine trials are insufficient to present firm conclusions about the properties of this antipsychotic. It is possible that perazine is associated with a similar risk of extrapyramidal side effects as some atypical antipsychotics but this is based on few comparisons of limited power.[1]


See also

External links

  1. ^ a b Leucht, S; Helfer, B; Hartung, B (2014). "Perazine for schizophrenia". Cochrane Database of Systematic Reviews. 1: CD002832.pub2. doi:10.1002/14651858.CD002832.pub3. 
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