Metanephrine

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Metanephrine
3-Methoxyadrenalin Structural Formulae V.1.svg
Names
IUPAC name
4-(1-hydroxy-2-methylamino-ethyl)-2-methoxy-phenol
Identifiers
  • 5001-33-2 ☑Y
3D model (JSmol)
  • Interactive image
ChEMBL
  • ChEMBL775 ☑Y
ChemSpider
  • 19844 ☑Y
  • 6644
MeSH Metanephrine
PubChem CID
  • 21100
Properties
C10H15NO3
Molar mass 197.231 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Metanephrine (metadrenaline) is a metabolite of epinephrine (adrenaline) created by action of catechol-O-methyl transferase on epinephrine. An article in the Journal of the American Medical Association, 2002, indicated that the measurement of plasma free levels of the metanephrines group of molecules (including metanephrine and normetanephrine) is the best tool in the diagnosis of pheochromocytoma, an adrenal medullary neoplasm.[1]

References

  1. ^ Lenders J, Pacak K, Walther M, Linehan W, Mannelli M, Friberg P, Keiser H, Goldstein D, Eisenhofer G (2002). "Biochemical diagnosis of pheochromocytoma: which test is best?". JAMA. 287 (11): 1427–34. doi:10.1001/jama.287.11.1427. PMID 11903030. Free full text with registration


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