From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Aliases KRT33A, HA3I, Ha-3I, K33A, KRTHA3A, Krt1-3, hHa3-I, keratin 33A
External IDs OMIM: 602761 HomoloGene: 135742 GeneCards: KRT33A
Gene location (Human)
Chromosome 17 (human)
Chr. Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for KRT33A
Genomic location for KRT33A
Band 17q21.2 Start 41,346,092 bp[1]
End 41,350,828 bp[1]
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 17: 41.35 – 41.35 Mb n/a
PubMed search [2] n/a
View/Edit Human

Keratin, type I cuticular Ha3-I is a protein that in humans is encoded by the KRT33A gene.[3][4][5]

The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRTHA3A and KRTHA3B.[5]


  1. ^ a b c ENSG00000006059 GRCh38: Ensembl release 89: ENSG00000261986, ENSG00000006059 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Rogers MA, Schweizer J, Kreig T, Winter H (Nov 1995). "A novel human type I hair keratin gene: evidence for two keratin hHa3 isoforms". Mol Biol Rep. 20 (3): 155–61. doi:10.1007/BF00990548. PMID 7565656.
  4. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
  5. ^ a b "Entrez Gene: KRT33A keratin 33A".

Further reading

Retrieved from ""
This content was retrieved from Wikipedia :
This page is based on the copyrighted Wikipedia article "KRT33A"; it is used under the Creative Commons Attribution-ShareAlike 3.0 Unported License (CC-BY-SA). You may redistribute it, verbatim or modified, providing that you comply with the terms of the CC-BY-SA