International System for Human Cytogenetic Nomenclature

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The International System for Human Cytogenetic Nomenclature (ISCN) is an international standard for human chromosome nomenclature, which includes band names, symbols and abbreviated terms used in the description of human chromosome and chromosome abnormalities.

The ISCN used as the central reference among cytogeneticists since 1960.[1][2]

Revision history

  • ISCN (2016). S. Karger Publishing. ISBN 978-3318058574
  • ISCN (2013). S. Karger Publishing. ISBN 978-3318022537
  • ISCN (2009). S. Karger Publishing. ISBN 978-3805589857
  • ISCN (2005). S. Karger Publishing. ISBN 978-3805580199
  • ISCN (1995). S. Karger Publishing. ISBN 978-3805562263
  • ISCN (1991). S. Karger Publishing. ISBN 978-3805555678
  • ISCN (1985). S. Karger Publishing. ISBN 978-3805538701
  • ISCN (1981). S. Karger Publishing. ISBN 978-3805534840
  • ISCN (1978). S. Karger Publishing. ISBN 978-3805530118
  • Paris Conference (1971): "Standardization in Human Cytogenetics." (PDF) Birth Defects: Original Article Series, Vol 8, No 7 (The National Foundation, New York 1972)
  • Chicago Conference (1966): "Standardization in Human Cytogenetics." Birth Defects: Original Article Series, Vol 2, No 2 (The National Foundation, New York 1966).
  • London Conference (1963): "London Conference on the Normal Human Karyotype." Cytogenetics 2:264–268 (1963)
  • Denver Conference (1960): "A proposed standard system of nomenclature of human mitotic chromosomes." The Lancet 275.7133 (1960): 1063-1065.


  1. ^ Slovak M.L., Theisen A., Shaffer L.G. (2013) "Human Chromosome Nomenclature: An Overview and Definition of Terms." In: Gersen S., Keagle M. (eds) The Principles of Clinical Cytogenetics. Springer, New York, NY doi:10.1007/978-1-4419-1688-4_3
  2. ^ Brothman AR, Persons DL, Shaffer LG (2009). "Nomenclature evolution: Changes in the ISCN from the 2005 to the 2009 edition". Cytogenet Genome Res. 127 (1): 1–4. doi:10.1159/000279442. PMID 20110655.CS1 maint: Multiple names: authors list (link)

See also

External links

  • About the ISCN recommendations - Human Genome Variation Society
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