FAM19A5

From Wikipedia, the free encyclopedia
FAM19A5
Identifiers
Aliases FAM19A5, QLLK5208, TAFA-5, TAFA5, UNQ5208, family with sequence similarity 19 (chemokine (C-C motif)-like), member A5, family with sequence similarity 19 member A5, C-C motif chemokine like
External IDs MGI: 2146182 HomoloGene: 22888 GeneCards: FAM19A5
Gene location (Human)
Chromosome 22 (human)
Chr. Chromosome 22 (human)[1]
Chromosome 22 (human)
Genomic location for FAM19A5
Genomic location for FAM19A5
Band 22q13.32 Start 48,489,460 bp[1]
End 48,850,912 bp[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015381
NM_001082967

NM_001252310
NM_134096

RefSeq (protein)

NP_001076436
NP_056196

NP_001239239
NP_598857

Location (UCSC) Chr 22: 48.49 – 48.85 Mb Chr 22: 87.63 – 87.76 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Protein FAM19A5 is a protein that in humans is encoded by the FAM19A5 gene.[5][6]

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000219438 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000054863 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Tom Tang Y, Emtage P, Funk WD, Hu T, Arterburn M, Park EE, Rupp F (Mar 2004). "TAFA: a novel secreted family with conserved cysteine residues and restricted expression in the brain". Genomics. 83 (4): 727–34. PMID 15028294. doi:10.1016/j.ygeno.2003.10.006. 
  6. ^ a b "Entrez Gene: FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5". 

Further reading


Retrieved from "https://en.wikipedia.org/w/index.php?title=FAM19A5&oldid=798127846"
This content was retrieved from Wikipedia : http://en.wikipedia.org/wiki/FAM19A5
This page is based on the copyrighted Wikipedia article "FAM19A5"; it is used under the Creative Commons Attribution-ShareAlike 3.0 Unported License (CC-BY-SA). You may redistribute it, verbatim or modified, providing that you comply with the terms of the CC-BY-SA