Eticyclidine

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Eticyclidine
Eticyclidine.svg
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
  • 2201-15-2 ☑Y
PubChem CID
  • 16622
ChemSpider
  • 15759 ☑Y
UNII
  • O8I1LL6A89
ChEMBL
  • CHEMBL279924 ☑Y
Chemical and physical data
Formula C14H21N
Molar mass 203.323 g/mol
3D model (JSmol)
  • Interactive image
  (verify)

Eticyclidine (PCE, CI-400) is a dissociative anesthetic drug with hallucinogenic effects. It is similar in effects to phencyclidine but is slightly more potent. PCE was developed by Parke-Davis in the 1970s and evaluated for anesthetic potential under the code name CI-400,[1] but research into PCE was not continued after the development of ketamine, a similar drug with more favourable properties.[2] PCE is slightly more potent than PCP and has similar effects, but its unpleasant taste and tendency to cause nausea made it less accepted by users.[3] Due to its similarity in effects to PCP, PCE was placed into the Schedule 1 list of illegal drugs in the 1970s, although it was only briefly abused in the 1970s and 1980s and is now little known.

See also

References

  1. ^ LEVY L, CAMERON DE, AITKEN RC (March 1960). "Observation on two psychotomimetic drugs of piperidine derivation--CI 395 (sernyl) and CI 400". The American Journal of Psychiatry. 116: 843–4. doi:10.1176/ajp.116.9.843. PMID 14416411.
  2. ^ Kalir A, Edery H, Pelah Z, Balderman D, Porath G. 1-Phenylcycloalkylamine derivatives. II. Synthesis and pharmacological activity. Journal of Medicinal Chemistry. 1969. 12(3):473-477
  3. ^ Structure Activity of PCP analogs


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