Etafedrine

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Etafedrine
Etafedrine.svg
Clinical data
ATC code
  • none
Legal status
Legal status
  • Withdrawn from market
Identifiers
CAS Number
  • 7681-79-0 ☑Y
PubChem CID
  • 10734
ChemSpider
UNII
  • 2Y6VQU63E8
ECHA InfoCard 100.051.218
Chemical and physical data
Formula C12H19NO
Molar mass 193.285 g/mol
3D model (JSmol)
  • Interactive image
 ‹See TfM›☒N☑Y (what is this?)   (verify)

Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has the brand name Nethaprin. It was previously commercially available as both the free base and as the hydrochloride salt from Sanofi-Aventis (now Sanofi) but is now no longer marketed.

Pharmacology

Unlike ephedrine and tyramine, etafedrine does not induce the release of epinephrine or norepinephrine and instead acts as a selective β2 adrenoreceptor agonist, thereby mediating its bronchodilator effects.[1]

See also

References

  1. ^ Lindmar, R; Löffelholz, K; Stieh-Koch, U (1985). "On the mechanism of bronchodilatation by etafedrine". Arzneimittel-Forschung. 35 (3): 602–4. PMID 4039586.
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