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Clinical data
Synonyms 2,5-Dimethoxy-4-propylamphetamine
Legal status
Legal status
CAS Number
  • 63779-88-4 ☒N
    53581-55-8 (hydrochloride)
PubChem CID
  • 542051
  • 472021 ☑Y
  • ChEMBL8569 ☑Y
CompTox Dashboard (EPA)
  • DTXSID40337347
Chemical and physical data
Formula C14H23NO2
Molar mass 237.34 g/mol g·mol−1
3D model (JSmol)
  • Interactive image
 ☒N☑Y (what is this?)   (verify)

2,5-Dimethoxy-4-propylamphetamine (DOPR) is a psychedelic drug of the phenethylamine and amphetamine chemical classes. It was first synthesized by Alexander Shulgin, and was described in his book PiHKAL (Phenethylamines i Have Known And Loved). Shulgin described DOPR is a "heavy duty psychedelic", complete with alterations of the thought process and visual distortion.[1] Very little data exists about the pharmacological properties, metabolism, and toxicity of DOPR.

The alternative structural isomer DOIP, with a 4-isopropyl substitution, is also known but is around ten times weaker than DOPR, with an active dose of some 20–30 mg (as compared to 2–5 mg for DOPR).[1]

Structure of DOIP

See also


  1. ^ a b Shulgin, Alexander; Shulgin, Ann (September 1991). PiHKAL: A Chemical Love Story. United States: Transform Press. p. 978. ISBN 0-9630096-0-5.

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