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DMeOB structure.png
Space-filling model of the DMeOB
CAS Number
  • 40252-74-2 ☑Y
PubChem CID
  • 6891506
  • 5277863 ☒N
CompTox Dashboard (EPA)
  • DTXSID10425967
ECHA InfoCard 100.164.778
Chemical and physical data
Formula C16H16N2O2
Molar mass 268.310 g/mol g·mol−1
3D model (JSmol)
  • Interactive image
 ☒N☑Y (what is this?)   (verify)

DMeOB is a drug used in scientific research which acts as a negative allosteric modulator of the metabotropic glutamate receptor subtype mGluR5.[1]


  1. ^ O'Brien JA, Lemaire W, Chen TB, Chang RS, Jacobson MA, Ha SN, Lindsley CW, Schaffhauser HJ, Sur C, Pettibone DJ, Conn PJ, Williams DL (September 2003). "A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5". Molecular Pharmacology. 64 (3): 731–40. doi:10.1124/mol.64.3.731. PMID 12920211.

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