Collagen, type XII, alpha 1

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Aliases COL12A1, BA209D8.1, COL12A1L, DJ234P15.1, BTHLM2, UCMD2, collagen type XII alpha 1, collagen type XII alpha 1 chain, EDSMYP
External IDs OMIM: 120320 MGI: 88448 HomoloGene: 3217 GeneCards: COL12A1
Gene location (Human)
Chromosome 6 (human)
Chr. Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for COL12A1
Genomic location for COL12A1
Band 6q13-q14.1 Start 75,084,326 bp[1]
End 75,206,051 bp[1]
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 6: 75.08 – 75.21 Mb Chr 9: 79.6 – 79.72 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

Collagen alpha-1(XII) chain is a protein that in humans is encoded by the COL12A1 gene.[5][6]

This gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified.[6]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000111799 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032332 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Gerecke DR, Olson PF, Koch M, Knoll JH, Taylor R, Hudson DL, Champliaud MF, Olsen BR, Burgeson RE (Jul 1997). "Complete primary structure of two splice variants of collagen XII, and assignment of alpha 1(XII) collagen (COL12A1), alpha 1(IX) collagen (COL9A1), and alpha 1(XIX) collagen (COL19A1) to human chromosome 6q12-q13". Genomics. 41 (2): 236–42. doi:10.1006/geno.1997.4638. PMID 9143499.
  6. ^ a b "Entrez Gene: COL12A1 collagen, type XII, alpha 1".

Further reading

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