Cloroqualone

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Cloroqualone
Cloroqualone.svg
Clinical data
Pregnancy
category
  •  ?
Routes of
administration
?
ATC code
  • none
Pharmacokinetic data
Bioavailability ?
Metabolism ?
Elimination half-life ?
Excretion ?
Identifiers
CAS Number
PubChem CID
  • 63338
DrugBank
ChemSpider
  • 57005 ☑Y
UNII
  • 172D4Q6LOW
ChEMBL
ECHA InfoCard 100.042.761
Chemical and physical data
Formula C16H12Cl2N2O
Molar mass 319.185
3D model (JSmol)
  • Interactive image
 ‹See TfM›☒N☑Y (what is this?)   (verify)

Cloroqualone is a quinazolinone-class GABAergic and is an analogue of methaqualone developed in the 1980s and marketed mainly in France and some other European countries. It has sedative and antitussive properties resulting from its agonist activity at the β subtype of the GABAa receptor and sigma-1 receptor, and was sold either alone or in combination with other ingredients as a cough medicine. Cloroqualone has weaker sedative properties than methaqualone and was sold for its useful cough-suppressing effects, but was withdrawn from the French market in 1994 because of concerns about its potential for abuse and overdose.

See also

References



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