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Drzewko rozwojowe komórek macierzystych krwi.JPG
Lineage. Captions in Polish, but "GMP" visible near bottom center.
Gives rise to Monoblasts and myeloblasts
Location Bone marrow
Function colony forming unit
TH H2.
Anatomical terms of microanatomy
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CFU-GM (or "GMP", for "granulocyte-macrophage progenitor") is a colony forming unit. It is derived from CFU-GEMM.

The "GM" stands for "granulocyte, monocyte".[1]

It is the precursor for monoblasts and myeloblasts.

Production is stimulated by granulocyte macrophage colony-stimulating factor (GM-CSF).


There is some controversy over which granulocytes derive from CFU-GM.

  • There is little disagreement that neutrophils come from CFU-GM.
  • Some sources state that basophils also derive from CFU-GM, but that eosinophils come from "CFU-Eos".[2]
  • Other sources state that basophils do not derive from CFU-GM, but from a distinct CFU, titled "CFU-Baso".[3]

See also


  1. ^ "Hem I WBC Morphology and Physiology". Archived from the original on December 25, 2008. Retrieved 2008-12-30.
  2. ^ Ganong, William F.; McPhee, Stephen J.; Lingappa, Vishwanath R. (2005). Pathophysiology of Disease: An Introduction to Clinical Medicine (Lange). McGraw-Hill Medical. p. 107. ISBN 0-07-144159-X.
  3. ^ Rudolph, Colin David (2003). Rudolph's pediatrics. New York: McGraw-Hill, Medical Pub. Division. p. 1563. ISBN 0-8385-8285-0.

External links

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