Alopecia totalis

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Alopecia totalis
A woman with alopecia totalis
Specialty Dermatology 

Alopecia totalis is the loss of all skull and facial hair. Its causes are unclear, but believed to be autoimmune.


Methotrexate and corticosteroids are proposed treatments.[1]

Scalp cooling has specifically been used to prevent alopecia in docetaxel chemotherapy,[2] although it has been found prophylactic in other regimens as well.[3][4][5] Treatment effects may take time to resolve, with one study showing breast cancer survivors wearing wigs up to 2 years after chemotherapy.[6]

See also


  1. ^ Joly, Pascal (2006). "The use of methtrexate alone or in combination with low doses of oral corticosteroids in the treatment of alopecia totalis or universalis". Journal of the American Academy of Dermatology. 55 (4): 632–6. doi:10.1016/j.jaad.2005.09.010. PMID 17010743.
  2. ^ Hurk, C. J. G.; Breed, W. P. M.; Nortier, J. W. R. (2012). "Short post-infusion scalp cooling time in the prevention of docetaxel-induced alopecia". Supportive Care in Cancer. 20 (12): 3255–3260. doi:10.1007/s00520-012-1465-0. PMID 22539051.
  3. ^ Lemieux, J. (2012). "Reducing chemotherapy-induced alopecia with scalp cooling". Clinical Advances in Hematology & Oncology. 10 (10): 681–682. PMID 23187775.
  4. ^ Van Den Hurk, C. J.; Peerbooms, M.; Van De Poll-Franse, L. V.; Nortier, J. W.; Coebergh, J. W. W.; Breed, W. P. (2012). "Scalp cooling for hair preservation and associated characteristics in 1411 chemotherapy patients - Results of the Dutch Scalp Cooling Registry". Acta Oncologica. 51 (4): 497–504. doi:10.3109/0284186X.2012.658966. PMID 22304489.
  5. ^ Yeager, C. E.; Olsen, E. A. (2011). "Treatment of chemotherapy-induced alopecia". Dermatologic Therapy. 24 (4): 432–442. doi:10.1111/j.1529-8019.2011.01430.x. PMID 21910801.
  6. ^ Oshima, Y.; Watanabe, T.; Nakagawa, S.; Endo, A.; Shiga, C. (2012). "A questionnaire survey about hair loss after chemotherapy for breast cancer". Gan to kagaku ryoho. Cancer & chemotherapy. 39 (9): 1375–1378. PMID 22996772.

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