4-Methoxyestrone

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4-Methoxyestrone
4-Methoxyestrone.svg
Names
IUPAC name
(8R,9S,13S,14S)-3-Hydroxy-4-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
Other names
4-ME1; 4-MeOE1; 4-MeO-E1; 4-Hydroxyestrone 4-methyl ether; 3-Hydroxy-4-methoxyestra-1,3,5(10)-trien-17-one
Identifiers
  • 58562-33-7
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:136972
ChEMBL
  • ChEMBL1627349
ChemSpider
  • 168393
PubChem CID
  • 194066
Properties
C19H24O3
Molar mass 300.40 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

4-Methoxyestrone (4-ME1) is an endogenous, naturally occurring methoxylated catechol estrogen and metabolite of estrone that is formed by catechol O-methyltransferase via the intermediate 4-hydroxyestrone.[1][2][3] It has estrogenic activity similarly to estrone and 4-hydroxyestrone.[4]

See also

References

  1. ^ http://www.hmdb.ca/metabolites/HMDB60088
  2. ^ Anna R. Hemnes (16 December 2015). Gender, Sex Hormones and Respiratory Disease: A Comprehensive Guide. Humana Press. pp. 32–. ISBN 978-3-319-23998-9. 
  3. ^ Christian Lauritzen; John W. W. Studd (22 June 2005). Current Management of the Menopause. CRC Press. pp. 378–379. ISBN 978-0-203-48612-2. 
  4. ^ Bhavnani BR, Nisker JA, Martin J, Aletebi F, Watson L, Milne JK (2000). "Comparison of pharmacokinetics of a conjugated equine estrogen preparation (premarin) and a synthetic mixture of estrogens (C.E.S.) in postmenopausal women". J. Soc. Gynecol. Investig. 7 (3): 175–83. doi:10.1016/s1071-5576(00)00049-6. PMID 10865186. 

External links

  • Metabocard for 4-Methoxyestrone - Human Metabolome Database



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