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Clinical data
Synonyms 1,3-benzodioxolyl-5-ethanamine;
Routes of
Legal status
Legal status
CAS Number
  • 1484-85-1 ☑Y
PubChem CID
  • 73874
  • 66508
ECHA InfoCard 100.014.601
Chemical and physical data
Formula C9H11NO2
Molar mass 165.18914 g/mol g·mol−1
3D model (JSmol)
  • Interactive image

3,4-Methylenedioxyphenethylamine ("3,4-MDPEA" or just "MDPEA"), also known as homopiperonylamine, is a substituted phenethylamine formed by adding a methylenedioxy group to phenethylamine. It is structurally similar to MDA, but without the methyl group at the alpha position.

According to Alexander Shulgin in his book PiHKAL, MDPEA appears to be biologically inactive. This is likely because of extensive first-pass metabolism by the enzyme monoamine oxidase. However, if MDPEA were either used in high enough of doses (e.g., 1-2 grams), or in combination with a monoamine oxidase inhibitor (MAOI), it is probable that it would become sufficiently active, though it would likely have a relatively short duration of action. This idea is similar in concept to the use of selective MAOA inhibitors and selective MAOB inhibitors in augmentation of dimethyltryptamine (DMT) and phenethylamine (PEA), respectively.

See also


  1. ^ "Ustawa z dnia 15 kwietnia 2011 r. o zmianie ustawy o przeciwdziałaniu narkomanii ( Dz.U. 2011 nr 105 poz. 614 )". Internetowy System Aktów Prawnych. Retrieved 17 June 2011.

External links

  • PiHKAL: #115 MDPEA; 3,4-Methylenedioxyphenethylamine; Homopiperonylamine
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