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Clinical data
Synonyms 11β,18-epoxy-21-hydroxypregn-4-ene-3,20-dione
Drug class Antimineralocorticoid
PubChem CID
  • 188963
Chemical and physical data
Formula C21H28O4
Molar mass 344.451 g/mol
3D model (JSmol)
  • Interactive image

18-Deoxyaldosterone is a steroidal antimineralocorticoid with mixed agonistantagonist but predominantly antagonistic activity at the mineralocorticoid receptor.[1]


  1. ^ Duax, William L.; Griffin, Jane F.; Strong, Phyllis D.; Funder, John W.; Ulick, Stanley (1982). "Molecular structure of 18-deoxyaldosterone and its relationship to receptor binding and activity". Journal of the American Chemical Society. 104 (25): 7291–7293. doi:10.1021/ja00389a063. ISSN 0002-7863.

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